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  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms
  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms
  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms
  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms
  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms
  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms
  • VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms

VSL#3 Probiotics for Digestive Health, IBS & UC Symptoms

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  • Trusted by Gastroenterologists:Recommended by experts for gut health in both men and women.
  • High Potency Per Capsule:Delivers 112.5 billion CFU of live probiotics.
  • 8-Strain Scientific Formula:Designed to restore balance and ease bloating and irregularity.
  • Dairy-Free & Allergen-Free:Contains no dairy, gluten, nuts, or GMOs. Vegan, kosher, and halal certified.
BENEFITS
  • Clinically supported: Backed by scientific research and trusted by healthcare professionals.
  • Utra -high-potency, muti strain blend： 112.5 bilion CFU per capsule from 8 complementary probiotic strains to help maintain a balanced intestinal microbiota
  • Refrigerated to preserve potency: Stored and shipped cold to ensure live cultures stay potent throughout shelf life.
  • Precisely manufactured: Produced under GMP-certified conditions, free from dairy, gluten, and other common iritants.
HOW TO USE
  • Typical adult dosage is 1-2 capsules up to 4 times daily, or as directed by a physician.
  • Swallow whole or mix into a non-carbonated cold beverage or food. Avoid consuming with hot foods or drinks,as heat may reduce probiotic viability.
  • Consistent use for several weeks may be needed to support microbiota balance.
  • For more information on how to take VSL#3 for the dietary management of certain GI conditions, please see the VSL#3 Product information.
  • SheetVSL#3 is a medical food intended to be used under medical supervision.
INGREDIENTS
  • Probiotic strains: Streptococcus thermophilus, Bifidobacterium breve, Bifdobacterium lactis (previously dasified as B. longum, Bifidobacterium lactis (previously dlassifed as B. infantis), Lactobacilus acidophilus, Lactobacils plantarum, Lactobacllus paracasei, Lactobacllus helveticus (previously dlassifed as L delbrueckii subsp. bulgaricus)
  • Other ingredients: Vegetal capsule (hydroxypropyl methylcellulose), cornstarch, magnesium stearate, slicon dioxide, stearic acid, microcrystaline celulose.

More Than a Probiotic. A Powerful Medical Food.

Pioneers in Probiotics.
Leaders in Gut Health.

VSL#3@ is an ultra-high-potency probiotic medical food - and the #1 gastroenterologist-recommended multi-strain probiotics brand.t Developed for people with serious gastrointestinal conditions, it's trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.

More Than a Probiotic. A Powerful Medical Food.

Built on Science.
Proven in Practice.

Driven by research - not marketing trends - VSL#3 is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.

More Than a Probiotic. A Powerful Medical Food.

Clinically Researched Formulas.
Real-World Results.

Each VSL#3 product combines 8 well-characterized probiotic strains from 3 genera to help maintain a balanced intestinal microbiota and support digestive health. The VSL#3 family is specially designed for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and pouchitis.

More Than a Probiotic. A Powerful Medical Food.

Ultra-High-Potency.
Guaranteed.

VSL#3 products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3 guarantees potency through expiration when stored as directed.

Why Doctors Trust VSL#3

  • "The best product for IBD. I strongly recommend VSL#3.“

    Dr. Victor Gallo
    Garden City Colon and Rectal Surgery Practice - Garden City, NY

  • "I recommend VSL#3R for maintenance of a healthy gut microbiome."

    Dr. George Barret MD
    Founder and Chief of Gastroenterology Beth Israel Deaconess Hospital - Milton, MA

  • "I've had great success in using VSL#3R post colonoscopy, and especially so in my IBS and UC patients."

    Dr. William Andy Shaver MD
    Gastroenterologist - Lubbock, TX

VSL#3 Is Scientifically Formulated For The Dietary Management of IBS

Doctor Recommended

In a 2002 survey of gastroenterologists, 93% reported that IBS patients were satisfied with VSL#3.1

The most frequently observed benefits:

  • Less bloating
  • Reduced pain
  • Better stool consistency and frequency
  • Overall symptom improvement

Clinically Studied and FODMAP Friendly Certified for the Dietary Management of IBS
In a 2021 clinical study, VSL#3@ showed outcomes comparable to those achieved with a low FODMAP diet2 - a commonly recommended but restrictive approach. Because VSL#3@ is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

It's What's on the Inside

  • Bifidobacterium

    Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. infantis), Bifidobacterium lactis (previously classified
    as B. longum)

  • Lactobacillus

    Lactobacillus acidophilus, Lactobacillus helveticus (previously classified as L. delbruecki subsp. bulgaricus),
    Lactobacillus paracasei, Lactobacillus
    plantarum

  • Streptococcus

    Streptococcus thermophilus

VSL#3 Capsules: Clean Ingredients. Verified Quality.

Free From Common Irritants:

  • Dairy-Free
  • Gluten-Free
  • Soy-Free
  • Nut-Free
  • No GMOs
  • Vegan

Certified for Peace of Mind:

  • FODMAP Friendly Certified
  • Halal Certified
  • Kosher Certified

Customer reviews

  • ★★★★★
    Really calms my Gut. I'm so thankful mydoctor recommended this product! It workswell everyday.
    Carol F.
  • ★★★★★
    Can't live without it! Keeps my digestivesystem in its lane and I don't have to be onedge all the time about getting sick after ...
    Awilda G.
  • ★★★★★
    Absolutely the best probiotic ave ever taken. I have had ssues with my gut for years and n over the counter probiotics have helped except VSL. This stuf realy works.
    Debra L.
  • ★★★★★
    Your VSL 3 hes neled meto Ive with coltis 've been abe to leam what to at and what no to eat to keep me regular, 'm back n the gadf course and hapy. Thanks for the lions of stuff in VSL3.
    William P.

FAQs

  • VSL#3 is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).

  • VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.

  • Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.

  • In a 2021 clinical study, VSL##3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 - a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.

    1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.

  • Although both products contain the same 8 probiotic strains, they are formulated and labeled for different purposes. VSL#3 is a refrigerated, ultra-high-potency probiotic medical food for the dietary management of specific GI conditions. VSL4 Gut is a probiotic supplement designed to support digestive comfort, regularity, and overall gut health.*