VSL@ Probiotics: A Legacy of Science in Every Strain.
Data suggest that greater bacterial diversity supports better gut health.
VSL#3 capsules contains 8 probiotic strains from 3 different genera, specifically chosen for their individual and complementary characteristics related to gut health.
8 Probiotic Strains 112.5B CFU Per Capsule
- Streptococcus thermophilus
- Bifidobacterium breve
- Bifidobacterium lactis**
- Bifidobacterium lactis***
- Lactobacillus acidophilus
- Lactobacillus plantarum
- Lactobacillus paracasei
- Lactobacillus helveticus****
Science Over Hype. Purpose Over Promises.
Built on the legacy of VSL#3 a probiotic trusted by healthcare professionals and recognized for its scientific rigor — VSL Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness.
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Designed for Viability
Carefully designed formulations that help safeguard live bacteria from production to delivery.
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Designed for Viability
Carefully designed formulations that help safeguard live bacteria from production to delivery.
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Science-Led Strain Selection
Thoughtfully formulated with complementary probiotic strains chosen for function and purpose.
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A Legacy of Expertise
A probiotic heritage recognized for its consistency, credibility, and professional trust.
Clean Ingredients. Trusted Standards.
The VSL Probiotics Difference
Medical Foods & Supplements
From medical foods formulated for the dietary management of Gl conditions to supplements for daily wellness, VSL Probiotics is made to the highest standards of quality and consistency.
The VSL Probiotics Difference
Proven Potency
Up to 900 billion live bacteria per serving - verified to maintain labeled CFU counts through expiration when stored as recommended.
The VSL Probiotics Difference
Evidence-Based Formulations
Formulated with probiotic strains and combinations supported by published research and guided by microbiome science.
The VSL Probiotics Difference
Trusted by Professionals
Rooted in the heritage of VSL#3—a probiotic trusted by healthcare professionals-VSL Probiotics carries that same dedication to quality and research into every new formulation.
FAQs
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VSL#3 is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).
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VSL#3 should be stored under refrigeration at 36-46°F (2-8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.
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Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.
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In a 2021 clinical study, VSL##3 demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet1 - a commonly recommended but restrictive approach. Because VSL#3 is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
1Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291. -
Although both products contain the same 8 probiotic strains, they are formulated and labeled for different purposes. VSL#3 is a refrigerated, ultra-high-potency probiotic medical food for the dietary management of specific GI conditions. VSL4 Gut is a probiotic supplement designed to support digestive comfort, regularity, and overall gut health.*